CRC 1208 Lecture
on Thursday, 30.06.2022,
4:30 pm- 6:00 p.m.
for all members of CRC 1208 and guests.

Cyrille Botte, ApicoLipid Group Head, CNRS, University of Grenoble, France
"Membrane biogenesis, host-parasite interaction and apicomplexa parasite survival: It’s all about lipids!"

Apicomplexa parasites are unicellular eukaryotes responsible for major human diseases that represent a massive burden, such as malaria and toxoplasmosis. These parasites are obligate intracellular parasites that have to invade, and depend on their host cell and the nutrients it provides, to survive and propagate. Current evidence shows that lipid synthesis and membrane biogenesis are crucial pathways for intracellular development. The success of Apicomplexa parasites relies on their capacity to adapt to the various physiological conditions of their host cells and their nutritional environment. How can the parasite control and orchestrate metabolic adaptation and lipid acquisition upon physiological and environmental changes in its host? Here, I will present our latest results showing the different metabolic and molecular strategies developed by the parasite for optimal intracellular development and propagation.

Host: Sven Gould